CD271-pluriBead anti-hu, 2 ml
current price: NT$3,210.00 – NT$4,500.00
The cells will be “touched” by the antibody. All the unwanted cells remain unbound and will be separated from the labeled and wanted cells in the following enrichment steps. The easiest way to hold back the labeled cells, when coupled to a solid phase, is to use cell strainer or magnets. The flow through is free of antibody-bound beads and can be used for another positive or negative cell enrichment. The enrichment with pluriBead can be done without any preparation of whole blood. The contamination with unbound cells especially platelets or erythrocytes is very low when the cells are directly isolated out of whole blood. The method fast, less expansive and results in a higher purity.
Category: Brands, Pluribeads
CD271 pluriBead suspension for the positive cell isolation of CD271+ target cells from any human sample material. (2ml)
The p75 neurotrophin receptor (p75NTR) – CD271 – was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR bound other neurotrophins equally well as Nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.
Bead | S-Bead, M-Bead |
---|---|
Storage Temperature | 4-8 °C |
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