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CD55 S-pluriBead anti-hu, 2 ml
current price: NT$3,210.00 – NT$4,500.00
The cells will be “touched” by the antibody. All the unwanted cells remain unbound and will be separated from the labeled and wanted cells in the following enrichment steps. The easiest way to hold back the labeled cells, when coupled to a solid phase, is to use cell strainer or magnets. The flow through is free of antibody-bound beads and can be used for another positive or negative cell enrichment. The enrichment with pluriBead can be done without any preparation of whole blood. The contamination with unbound cells especially platelets or erythrocytes is very low when the cells are directly isolated out of whole blood. The method fast, less expansive and results in a higher purity.
CD55 pluriBead suspension for the positive cell isolation of CD55+ target cells from any human sample material. (2ml)
Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. DAF regulates the complement system on the cell surface. It recognizes C4b and C3b fragments that are created during activation of C4 (classical or lectin pathway) or C3 (alternative pathway). Interaction of DAF with cell-associated C4b of the classical and lectin pathways interferes with the conversion of C2 to C2b, thereby preventing formation of the C4b2a C3-convertase, and interaction of DAF with C3b of the alternative pathway interferes with the conversion of factor B to Bb by factor D, thereby preventing formation of the C3bBb C3 convertase of the alternative pathway. Thus, by limiting the amplification convertases of the complement cascade, DAF indirectly blocks the formation of the membrane attack complex
| Bead | S-Bead, M-Bead |
|---|---|
| Storage Temperature | 4-8 °C |
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