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CD3-pluriBead anti-hu, 2 ml
current price: NT$3,210.00 – NT$4,500.00
The cells will be “touched” by the antibody. All the unwanted cells remain unbound and will be separated from the labeled and wanted cells in the following enrichment steps. The easiest way to hold back the labeled cells, when coupled to a solid phase, is to use cell strainer or magnets. The flow through is free of antibody-bound beads and can be used for another positive or negative cell enrichment. The enrichment with pluriBead can be done without any preparation of whole blood. The contamination with unbound cells especially platelets or erythrocytes is very low when the cells are directly isolated out of whole blood. The method fast, less expansive and results in a higher purity.
CD2 pluriBead suspension for the positive cell isolation of CD3+ target cells from any human sample material. (2ml)
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098).
| Cell Type | |
|---|---|
| Species | |
| Bead | S-Bead, M-Bead |
| Storage Temperature | 4-8 °C |
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